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The Effects of CSF Neurogranin and APOE ε4 on Cognition and Neuropathology in Mild Cognitive Impairment and Alzheimer’s Disease

Cerebrospinal fluid (CSF) measurements of neurogranin (Ng) have emerged as a promising biomarker for cognitive decline in mild cognitive impairment (MCI) and Alzheimer’s disease (AD). The apolipoprotein E ε4 (APOE ε4) allele is by far the most consistent genetic risk factor for AD. However, it is no...

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Detalles Bibliográficos
Autores principales: Fan, Yulan, Gao, Ying, Therriault, Joseph, Luo, Jing, Ba, Maowen, Zhang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110906/
https://www.ncbi.nlm.nih.gov/pubmed/33986657
http://dx.doi.org/10.3389/fnagi.2021.667899