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Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population

Neural stem cell numbers fall rapidly in the hippocampus of juvenile mice but stabilize during adulthood, ensuring lifelong hippocampal neurogenesis. We show that this stabilization of stem cell numbers in young adults is the result of coordinated changes in stem cell behavior. Although proliferatin...

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Detalles Bibliográficos
Autores principales: Harris, Lachlan, Rigo, Piero, Stiehl, Thomas, Gaber, Zachary B., Austin, Sophie H.L., Masdeu, Maria del Mar, Edwards, Amelia, Urbán, Noelia, Marciniak-Czochra, Anna, Guillemot, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110946/
https://www.ncbi.nlm.nih.gov/pubmed/33581058
http://dx.doi.org/10.1016/j.stem.2021.01.003