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A synthetic RNA editing factor edits its target site in chloroplasts and bacteria

Members of the pentatricopeptide repeat (PPR) protein family act as specificity factors in C-to-U RNA editing. The expansion of the PPR superfamily in plants provides the sequence variation required for design of consensus-based RNA-binding proteins. We used this approach to design a synthetic RNA e...

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Detalles Bibliográficos
Autores principales: Royan, Santana, Gutmann, Bernard, Colas des Francs-Small, Catherine, Honkanen, Suvi, Schmidberger, Jason, Soet, Ashley, Sun, Yueming Kelly, Vincis Pereira Sanglard, Lilian, Bond, Charles S., Small, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110955/
https://www.ncbi.nlm.nih.gov/pubmed/33972654
http://dx.doi.org/10.1038/s42003-021-02062-9