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FMRP regulates STAT3 mRNA localization to cellular protrusions and local translation to promote hepatocellular carcinoma metastasis

Most hepatocellular carcinoma (HCC)-associated mortalities are related to the metastasis of cancer cells. The localization of mRNAs and their products to cell protrusions has been reported to play a crucial role in the metastasis. Our previous findings demonstrated that STAT3 mRNA accumulated in the...

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Detalles Bibliográficos
Autores principales: Shen, Zhifa, Liu, Bowen, Wu, Biting, Zhou, Hongyin, Wang, Xiangyun, Cao, Jinling, Jiang, Min, Zhou, Yingying, Guo, Feixia, Xue, Chang, Wu, Zai-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110961/
https://www.ncbi.nlm.nih.gov/pubmed/33972660
http://dx.doi.org/10.1038/s42003-021-02071-8