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Mucosal ribosomal stress-induced PRDM1 promotes chemoresistance via stemness regulation

The majorities of colorectal cancer (CRC) cases are sporadic in origin and a large proportion of etiologies are associated with environmental stress responses. In response to external and internal stress, the ribosome stands sentinel and stress-driven ribosomal dysfunction triggers the cellular deci...

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Detalles Bibliográficos
Autores principales: Kim, Juil, Moon, Yuseok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110964/
https://www.ncbi.nlm.nih.gov/pubmed/33972671
http://dx.doi.org/10.1038/s42003-021-02078-1