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Prion potentiation after life-long dormancy in mice devoid of PrP

Prions are neurotropic pathogens composed of misfolded assemblies of the host-encoded prion protein PrP(C) which replicate by recruitment and conversion of further PrP(C) by an autocatalytic seeding polymerization process. While it has long been shown that mouse-adapted prions cannot replicate and a...

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Detalles Bibliográficos
Autores principales:	Martin, Davy, Reine, Fabienne, Herzog, Laetitia, Igel-Egalon, Angélique, Aron, Naima, Michel, Christel, Moudjou, Mohammed, Fichet, Guillaume, Quadrio, Isabelle, Perret-Liaudet, Armand, Andréoletti, Olivier, Rezaei, Human, Béringue, Vincent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111064/ https://www.ncbi.nlm.nih.gov/pubmed/33997785 http://dx.doi.org/10.1093/braincomms/fcab092

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