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Histone Deacetylase Inhibitors Romidepsin and Vorinostat Promote Hepatitis B Virus Replication by Inducing Cell Cycle Arrest

BACKGROUND AND AIMS: Chronic hepatitis B virus (HBV) infection is a global public health challenge. HBV reactivation usually occurs in cancer patients after receiving cytotoxic chemotherapy or immunosuppressive therapies. Romidepsin (FK228) and vorinostat (SAHA) are histone deacetylase inhibitors (H...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Yan, Yu, Chen, Zhen, Hu, Jie, Wang, Kai, Tang, Ni, Li, Xiaosong, Zhou, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111102/
https://www.ncbi.nlm.nih.gov/pubmed/34007797
http://dx.doi.org/10.14218/JCTH.2020.00105