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Pathways and Mechanism of Caffeine Binding to Human Adenosine A(2A) Receptor
Caffeine (CFF) is a common antagonist to the four subtypes of adenosine G-protein-coupled receptors (GPCRs), which are critical drug targets for treating heart failure, cancer, and neurological diseases. However, the pathways and mechanism of CFF binding to the target receptors remain unclear. In th...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111288/ https://www.ncbi.nlm.nih.gov/pubmed/33987207 http://dx.doi.org/10.3389/fmolb.2021.673170 |