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Selective deletion of connective tissue growth factor attenuates experimentally-induced pulmonary fibrosis and pulmonary arterial hypertension

Connective tissue growth factor (CTGF, CCN2) is a matricellular protein which plays key roles in normal mammalian development and in tissue homeostasis and repair. In pathological conditions, dysregulated CCN2 has been associated with cancer, cardiovascular disease, and tissue fibrosis. In this stud...

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Detalles Bibliográficos
Autores principales: Tam, Angela Y.Y., Horwell, Amy L., Trinder, Sarah L., Khan, Korsa, Xu, Shiwen, Ong, Voon, Denton, Christopher P., Norman, Jill T., Holmes, Alan M., Bou-Gharios, George, Abraham, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111417/
https://www.ncbi.nlm.nih.gov/pubmed/33662577
http://dx.doi.org/10.1016/j.biocel.2021.105961