A pilot study of oral treprostinil pharmacogenomics and treatment persistence in patients with pulmonary arterial hypertension

BACKGROUND AND AIMS: Treprostinil is a prostacyclin analog used to treat pulmonary arterial hypertension. Dosing is empiric and based on tolerability. Adverse effects are common and can affect treatment persistence. Pharmacogenomic variants that may affect treprostinil metabolism and transport have...

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Detalles Bibliográficos
Autores principales: Coons, James C., Crisamore, Karryn, Adams, Solomon, Modany, Ashley, Simon, Marc A., Zhao, Wenchen, Shaik, Imam H., Venkataramanan, Raman, Empey, Philip E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111525/
https://www.ncbi.nlm.nih.gov/pubmed/33929912
http://dx.doi.org/10.1177/17534666211013688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111525/
https://www.ncbi.nlm.nih.gov/pubmed/33929912
http://dx.doi.org/10.1177/17534666211013688

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