Association of a Marker of N-Acetylglucosamine With Progressive Multiple Sclerosis and Neurodegeneration

IMPORTANCE: N-glycan branching modulates cell surface receptor availability, and its deficiency in mice promotes inflammatory demyelination, reduced myelination, and neurodegeneration. N-acetylglucosamine (GlcNAc) is a rate-limiting substrate for N-glycan branching, but, to our knowledge, endogenous...

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Detalles Bibliográficos
Autores principales: Brandt, Alexander U., Sy, Michael, Bellmann-Strobl, Judith, Newton, Barbara L., Pawling, Judy, Zimmermann, Hanna G., Yu, Zhaoxia, Chien, Claudia, Dörr, Jan, Wuerfel, Jens Th., Dennis, James W., Paul, Friedemann, Demetriou, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111565/
https://www.ncbi.nlm.nih.gov/pubmed/33970182
http://dx.doi.org/10.1001/jamaneurol.2021.1116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111565/
https://www.ncbi.nlm.nih.gov/pubmed/33970182
http://dx.doi.org/10.1001/jamaneurol.2021.1116

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