Retinal imaging demonstrates reduced capillary density in clinically unimpaired APOE ε4 gene carriers

INTRODUCTION: Apolipoprotein E (APOE) ε4, the strongest non‐Mendelian genetic risk factor for Alzheimer's disease (AD), has been shown to affect brain capillaries in mice, with potential implications for AD‐related neurodegenerative disease. However, human brain capillaries cannot be directly v...

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Detalles Bibliográficos
Autores principales: Elahi, Fanny M., Ashimatey, Senyo B., Bennett, Daniel J., Walters, Samantha M., La Joie, Renaud, Jiang, Xuejuan, Wolf, Amy, Cobigo, Yann, Staffaroni, Adam M., Rosen, Howie J., Miller, Bruce L., Rabinovici, Gil D., Kramer, Joel H., Green, Ari J., Kashani, Amir H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Retinal Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111703/
https://www.ncbi.nlm.nih.gov/pubmed/34013017
http://dx.doi.org/10.1002/dad2.12181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111703/
https://www.ncbi.nlm.nih.gov/pubmed/34013017
http://dx.doi.org/10.1002/dad2.12181

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