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Slit diaphragm maintenance requires dynamic clathrin-mediated endocytosis facilitated by AP-2, Lap, Aux and Hsc70-4 in nephrocytes
BACKGROUND: The Slit diaphragm (SD) is the key filtration structure in human glomerular kidney that is affected in many types of renal diseases. SD proteins are known to undergo endocytosis and recycling to maintain the integrity of the filtration structure. However, the key components of this pathw...
Autores principales: | Wang, Luyao, Wen, Pei, van de Leemput, Joyce, Zhao, Zhanzheng, Han, Zhe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111712/ https://www.ncbi.nlm.nih.gov/pubmed/33975644 http://dx.doi.org/10.1186/s13578-021-00595-4 |
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