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Novel leukocyte-depleted platelet-rich plasma-based skin equivalent as an in vitro model of chronic wounds: a preliminary study

BACKGROUND: Chronic leg ulcerations are associated with Haemoglobin disorders, Type2 Diabetes Mellitus, and long-term venous insufficiency, where poor perfusion and altered metabolism develop into a chronic inflammation that impairs wound closure. Skin equivalent organotypic cultures can be engineer...

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Detalles Bibliográficos
Autores principales: Seria, Elisa, Galea, George, Borg, Joseph, Schembri, Kevin, Grech, Gabriella, Tagliaferro, Sarah Samut, Felice, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111747/
https://www.ncbi.nlm.nih.gov/pubmed/33971814
http://dx.doi.org/10.1186/s12860-021-00366-6