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Novel leukocyte-depleted platelet-rich plasma-based skin equivalent as an in vitro model of chronic wounds: a preliminary study

BACKGROUND: Chronic leg ulcerations are associated with Haemoglobin disorders, Type2 Diabetes Mellitus, and long-term venous insufficiency, where poor perfusion and altered metabolism develop into a chronic inflammation that impairs wound closure. Skin equivalent organotypic cultures can be engineer...

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Detalles Bibliográficos
Autores principales:	Seria, Elisa, Galea, George, Borg, Joseph, Schembri, Kevin, Grech, Gabriella, Tagliaferro, Sarah Samut, Felice, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111747/ https://www.ncbi.nlm.nih.gov/pubmed/33971814 http://dx.doi.org/10.1186/s12860-021-00366-6

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