Evaluation of mitochondria in mouse oocytes following cisplatin exposure

BACKGROUND: Cisplatin is a platinum-based chemotherapeutic that damages genomic DNA leading to cell death. It also damages mitochondrial DNA and induces high levels of mitochondrial reactive oxygen species (mtROS), further sensitising cells to apoptosis. Notably, immature oocytes are particularly vu...

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Detalles Bibliográficos
Autores principales: Wang, Qiaochu, Hutt, Karla J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111953/
https://www.ncbi.nlm.nih.gov/pubmed/33971923
http://dx.doi.org/10.1186/s13048-021-00817-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111953/
https://www.ncbi.nlm.nih.gov/pubmed/33971923
http://dx.doi.org/10.1186/s13048-021-00817-w

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