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Evaluation of mitochondria in mouse oocytes following cisplatin exposure
BACKGROUND: Cisplatin is a platinum-based chemotherapeutic that damages genomic DNA leading to cell death. It also damages mitochondrial DNA and induces high levels of mitochondrial reactive oxygen species (mtROS), further sensitising cells to apoptosis. Notably, immature oocytes are particularly vu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111953/ https://www.ncbi.nlm.nih.gov/pubmed/33971923 http://dx.doi.org/10.1186/s13048-021-00817-w |