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Gambogic acid protects LPS-induced apoptosis and inflammation in a cell model of neonatal pneumonia through the regulation of TrkA/Akt signaling pathway

OBJECTIVE: In this work, we investigated the effects of gambogic acid (GA) on lipopolysaccharide (LPS)-induced apoptosis and inflammation in a cell model of neonatal pneumonia. METHOD: Human WI-38 cells were maintained in vitro and incubated with various concentrations of GA to examine WI-38 surviva...

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Detalles Bibliográficos
Autores principales: Gao, Xu, Dai, Jingya, Li, Guifang, Dai, Xinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112032/
https://www.ncbi.nlm.nih.gov/pubmed/33971977
http://dx.doi.org/10.1186/s40360-021-00496-9