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Anti-VEGF treatment suppresses remodeling factors and restores epithelial barrier function through the E-cadherin/β-catenin signaling axis in experimental asthma models
Besides maintaining a physical barrier with adherens junctional (AJ) and tight junctional proteins, airway epithelial cells have important roles in modulating the inflammatory processes of allergic asthma. E-cadherin and β-catenin are the key AJ proteins that are involved in airway remodeling. Vario...
Autores principales: | Türkeli, Ahmet, Yilmaz, Özge, Karaman, Meral, Kanik, Esra Toprak, Firinci, Fatih, İnan, Sevinç, Yüksel, Hasan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112133/ https://www.ncbi.nlm.nih.gov/pubmed/33986854 http://dx.doi.org/10.3892/etm.2021.10121 |
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