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Anti-VEGF treatment suppresses remodeling factors and restores epithelial barrier function through the E-cadherin/β-catenin signaling axis in experimental asthma models

Besides maintaining a physical barrier with adherens junctional (AJ) and tight junctional proteins, airway epithelial cells have important roles in modulating the inflammatory processes of allergic asthma. E-cadherin and β-catenin are the key AJ proteins that are involved in airway remodeling. Vario...

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Detalles Bibliográficos
Autores principales: Türkeli, Ahmet, Yilmaz, Özge, Karaman, Meral, Kanik, Esra Toprak, Firinci, Fatih, İnan, Sevinç, Yüksel, Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112133/
https://www.ncbi.nlm.nih.gov/pubmed/33986854
http://dx.doi.org/10.3892/etm.2021.10121