Using CRISPR/Cas9 System to Knock out Exon 48 in DMD Gene

BACKGROUND: Out of frame mutations in DMD gene cause Duchenne Muscular Dystrophy (DMD) which is a neuromuscular progressive genetic disorder. In DMD patients, lack of dystrophin causes progressive muscle degeneration, which results in heart and respiratory failure leading to premature death. At pres...

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Detalles Bibliográficos
Autores principales: Dara, Mahintaj, Razban, Vahid, Talebzadeh, Mahdieh, Moradi, Sepideh, Dianatpour, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112140/
https://www.ncbi.nlm.nih.gov/pubmed/34012519
http://dx.doi.org/10.18502/ajmb.v13i2.5517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112140/
https://www.ncbi.nlm.nih.gov/pubmed/34012519
http://dx.doi.org/10.18502/ajmb.v13i2.5517

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