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Using CRISPR/Cas9 System to Knock out Exon 48 in DMD Gene
BACKGROUND: Out of frame mutations in DMD gene cause Duchenne Muscular Dystrophy (DMD) which is a neuromuscular progressive genetic disorder. In DMD patients, lack of dystrophin causes progressive muscle degeneration, which results in heart and respiratory failure leading to premature death. At pres...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Avicenna Research Institute
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112140/ https://www.ncbi.nlm.nih.gov/pubmed/34012519 http://dx.doi.org/10.18502/ajmb.v13i2.5517 |