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Prediction of Synergistic Drug Combinations for Prostate Cancer by Transcriptomic and Network Characteristics

Prostate cancer (PRAD) is a major cause of cancer-related deaths. Current monotherapies show limited efficacy due to often rapidly emerging resistance. Combination therapies could provide an alternative solution to address this problem with enhanced therapeutic effect, reduced cytotoxicity, and dela...

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Detalles Bibliográficos
Autores principales: Li, Shiqi, Zhang, Fuhui, Xiao, Xiuchan, Guo, Yanzhi, Wen, Zhining, Li, Menglong, Pu, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112211/
https://www.ncbi.nlm.nih.gov/pubmed/33986671
http://dx.doi.org/10.3389/fphar.2021.634097