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Imprinted Genes Impact Upon Beta Cell Function in the Current (and Potentially Next) Generation

Beta cell failure lies at the centre of the aetiology and pathogenesis of type 2 diabetes and the epigenetic control of the expression of critical beta cell genes appears to play a major role in this decline. One such group of epigenetically-controlled genes, termed ‘imprinted’ genes, are characteri...

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Detalles Bibliográficos
Autores principales: Villanueva-Hayes, Chelsie, Millership, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112240/
https://www.ncbi.nlm.nih.gov/pubmed/33986727
http://dx.doi.org/10.3389/fendo.2021.660532