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Tocilizumab increases citrullinated histone 3 in non-ST segment elevation myocardial infarction

OBJECTIVE: Beyond reducing inflammation and troponin T (TnT) release, the interleukin-6 receptor antagonist tocilizumab reduces neutrophil counts in patients with non-ST segment elevation myocardial infarction (NSTEMI). It is unclear if this is related to formation of neutrophil extracellular traps...

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Detalles Bibliográficos
Autores principales: Helseth, Ragnhild, Kleveland, Ola, Ueland, Thor, Wiseth, Rune, Damas, Jan Kristian, Broch, Kaspar, Michelsen, Annika, Bendz, Bjørn, Gullestad, Lars, Aukrust, Pål, Seljeflot, Ingebjørg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112443/
https://www.ncbi.nlm.nih.gov/pubmed/33972404
http://dx.doi.org/10.1136/openhrt-2020-001492