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Use of a mutation-specific genotyping method to assess for HIV-1 drug resistance in antiretroviral-naïve HIV-1 Subtype C-infected patients in Botswana

Background: HIV-1 drug resistance poses a major threat to the success of antiretroviral therapy. The high costs of available HIV drug resistance assays prohibit their routine usage in resource-limited settings. Pan-degenerate amplification and adaptation (PANDAA), a focused genotyping approach based...

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Detalles Bibliográficos
Autores principales: Maruapula, Dorcas, MacLeod, Iain J., Moyo, Sikhulile, Musonda, Rosemary, Seatla, Kaelo, Molebatsi, Kesaobaka, Leteane, Melvin, Essex, Max, Gaseitsiwe, Simani, Rowley, Christopher F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112461/
https://www.ncbi.nlm.nih.gov/pubmed/34036243
http://dx.doi.org/10.12688/aasopenres.13107.2