UTX promotes CD8(+) T cell-mediated antiviral defenses but reduces T cell durability

Persistent virus infections can cause pathogenesis that is debilitating or lethal. During these infections, virus-specific T cells fail to protect due to weakened antiviral activity or failure to persist. These outcomes are governed by histone modifications, although it is unknown which enzymes cont...

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Detalles Bibliográficos
Autores principales: Mitchell, Joseph E., Lund, Makayla M., Starmer, Josh, Ge, Kai, Magnuson, Terry, Shpargel, Karl B., Whitmire, Jason K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112613/
https://www.ncbi.nlm.nih.gov/pubmed/33852868
http://dx.doi.org/10.1016/j.celrep.2021.108966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112613/
https://www.ncbi.nlm.nih.gov/pubmed/33852868
http://dx.doi.org/10.1016/j.celrep.2021.108966

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