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UTX promotes CD8(+) T cell-mediated antiviral defenses but reduces T cell durability
Persistent virus infections can cause pathogenesis that is debilitating or lethal. During these infections, virus-specific T cells fail to protect due to weakened antiviral activity or failure to persist. These outcomes are governed by histone modifications, although it is unknown which enzymes cont...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112613/ https://www.ncbi.nlm.nih.gov/pubmed/33852868 http://dx.doi.org/10.1016/j.celrep.2021.108966 |