A primary nasopharyngeal three-dimensional air-liquid interface cell culture model of the pseudostratified epithelium reveals differential donor- and cell type-specific susceptibility to Epstein-Barr virus infection

Epstein-Barr virus (EBV) is a ubiquitous γ-herpesvirus with latent and lytic cycles. EBV replicates in the stratified epithelium but the nasopharynx is also composed of pseudostratified epithelium with distinct cell types. Latent infection is associated with nasopharyngeal carcinoma (NPC). Here, we...

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Detalles Bibliográficos
Autores principales: Ziegler, Phillip, Tian, Yarong, Bai, Yulong, Abrahamsson, Sanna, Bäckerholm, Alan, Reznik, Alex S., Green, Anthony, Moore, John A., Lee, Stella E., Myerburg, Michael M., Park, Hyun Jung, Tang, Ka-Wei, Shair, Kathy Ho Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112674/
https://www.ncbi.nlm.nih.gov/pubmed/33914843
http://dx.doi.org/10.1371/journal.ppat.1009041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112674/
https://www.ncbi.nlm.nih.gov/pubmed/33914843
http://dx.doi.org/10.1371/journal.ppat.1009041

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