Genome-wide identification of 5-methylcytosine sites in bacterial genomes by high-throughput sequencing of MspJI restriction fragments

Single-molecule Real-Time (SMRT) sequencing can easily identify sites of N6-methyladenine and N4-methylcytosine within DNA sequences, but similar identification of 5-methylcytosine sites is not as straightforward. In prokaryotic DNA, methylation typically occurs within specific sequence contexts, or...

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Detalles Bibliográficos
Autores principales: Anton, Brian P., Fomenkov, Alexey, Wu, Victoria, Roberts, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112702/
https://www.ncbi.nlm.nih.gov/pubmed/33974631
http://dx.doi.org/10.1371/journal.pone.0247541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112702/
https://www.ncbi.nlm.nih.gov/pubmed/33974631
http://dx.doi.org/10.1371/journal.pone.0247541

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