Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies

The recently reported “UK variant” (B.1.1.7) of SARS-CoV-2 is thought to be more infectious than previously circulating strains as a result of several changes, including the N501Y mutation. We present a 2.9-Å resolution cryo-electron microscopy (cryo-EM) structure of the complex between the ACE2 rec...

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Detalles Bibliográficos
Autores principales: Zhu, Xing, Mannar, Dhiraj, Srivastava, Shanti S., Berezuk, Alison M., Demers, Jean-Philippe, Saville, James W., Leopold, Karoline, Li, Wei, Dimitrov, Dimiter S., Tuttle, Katharine S., Zhou, Steven, Chittori, Sagar, Subramaniam, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112707/
https://www.ncbi.nlm.nih.gov/pubmed/33914735
http://dx.doi.org/10.1371/journal.pbio.3001237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112707/
https://www.ncbi.nlm.nih.gov/pubmed/33914735
http://dx.doi.org/10.1371/journal.pbio.3001237

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