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Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies
The recently reported “UK variant” (B.1.1.7) of SARS-CoV-2 is thought to be more infectious than previously circulating strains as a result of several changes, including the N501Y mutation. We present a 2.9-Å resolution cryo-electron microscopy (cryo-EM) structure of the complex between the ACE2 rec...
Autores principales: | Zhu, Xing, Mannar, Dhiraj, Srivastava, Shanti S., Berezuk, Alison M., Demers, Jean-Philippe, Saville, James W., Leopold, Karoline, Li, Wei, Dimitrov, Dimiter S., Tuttle, Katharine S., Zhou, Steven, Chittori, Sagar, Subramaniam, Sriram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112707/ https://www.ncbi.nlm.nih.gov/pubmed/33914735 http://dx.doi.org/10.1371/journal.pbio.3001237 |
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