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Different patterns of p16(INK4a) immunohistochemical expression and their biological implications in laryngeal squamous cell carcinoma

Introduction: p16(INK4a) immunohistochemistry (IHC) is widely used to facilitate the diagnosis of human papillomavirus (HPV)-associated neoplasia, when ≥70% of cells show strong nuclear and cytoplasmic positivity. In this study, we aim to compare partial expression patterns that do not fulfill the a...

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Detalles Bibliográficos
Autores principales: Lazăr, Camelia-Sidonia, Şovrea, Alina Simona, Georgiu, Carmen, Crişan, Doiniţa, Mirescu, Ştefan-Claudiu, Cosgarea, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112783/
https://www.ncbi.nlm.nih.gov/pubmed/33817711
http://dx.doi.org/10.47162/RJME.61.3.08