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Compartment-specific opioid receptor signaling is selectively modulated by different dynorphin peptides

Many signal transduction systems have an apparent redundancy built into them, where multiple physiological agonists activate the same receptors. Whether this is true redundancy, or whether this provides an as-yet unrecognized specificity in downstream signaling, is not well understood. We address th...

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Detalles Bibliográficos
Autores principales: Kunselman, Jennifer M, Gupta, Achla, Gomes, Ivone, Devi, Lakshmi A, Puthenveedu, Manojkumar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112862/
https://www.ncbi.nlm.nih.gov/pubmed/33908346
http://dx.doi.org/10.7554/eLife.60270