The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains

Sigma 1 receptor (S1R) is a 223-amino-acid-long transmembrane endoplasmic reticulum (ER) protein. S1R modulates activity of multiple effector proteins and is a well-established drug target. However, signaling functions of S1R in cells are poorly understood. Here, we test the hypothesis that biologic...

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Detalles Bibliográficos
Autores principales: Zhemkov, Vladimir, Ditlev, Jonathon A, Lee, Wan-Ru, Wilson, Mikaela, Liou, Jen, Rosen, Michael K, Bezprozvanny, Ilya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112866/
https://www.ncbi.nlm.nih.gov/pubmed/33973848
http://dx.doi.org/10.7554/eLife.65192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112866/
https://www.ncbi.nlm.nih.gov/pubmed/33973848
http://dx.doi.org/10.7554/eLife.65192

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