Cargando…
The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains
Sigma 1 receptor (S1R) is a 223-amino-acid-long transmembrane endoplasmic reticulum (ER) protein. S1R modulates activity of multiple effector proteins and is a well-established drug target. However, signaling functions of S1R in cells are poorly understood. Here, we test the hypothesis that biologic...
Autores principales: | Zhemkov, Vladimir, Ditlev, Jonathon A, Lee, Wan-Ru, Wilson, Mikaela, Liou, Jen, Rosen, Michael K, Bezprozvanny, Ilya |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112866/ https://www.ncbi.nlm.nih.gov/pubmed/33973848 http://dx.doi.org/10.7554/eLife.65192 |
Ejemplares similares
-
Sigma 1 Receptor, Cholesterol and Endoplasmic Reticulum
Contact Sites
por: Zhemkov, Vladimir, et al.
Publicado: (2021) -
Mutational Analysis of Sigma-1 Receptor’s Role in Synaptic Stability
por: Ryskamp, Daniel A., et al.
Publicado: (2019) -
Sigma-1 Receptor (S1R) Interaction with Cholesterol: Mechanisms of S1R Activation and Its Role in Neurodegenerative Diseases
por: Zhemkov, Vladimir, et al.
Publicado: (2021) -
Neuronal Sigma-1 Receptors: Signaling Functions and Protective Roles in Neurodegenerative Diseases
por: Ryskamp, Daniel A., et al.
Publicado: (2019) -
Glycolipids: Linchpins in the Organization and Function of Membrane Microdomains
por: Hanafusa, Kei, et al.
Publicado: (2020)