Therapeutic inhibition of keratinocyte TRPV3 sensory channel by local anesthetic dyclonine

The multimodal sensory channel transient receptor potential vanilloid-3 (TRPV3) is expressed in epidermal keratinocytes and implicated in chronic pruritus, allergy, and inflammation-related skin disorders. Gain-of-function mutations of TRPV3 cause hair growth disorders in mice and Olmsted syndrome i...

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Detalles Bibliográficos
Autores principales: Liu, Qiang, Wang, Jin, Wei, Xin, Hu, Juan, Ping, Conghui, Gao, Yue, Xie, Chang, Wang, Peiyu, Cao, Peng, Cao, Zhengyu, Yu, Ye, Li, Dongdong, Yao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112869/
https://www.ncbi.nlm.nih.gov/pubmed/33876725
http://dx.doi.org/10.7554/eLife.68128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112869/
https://www.ncbi.nlm.nih.gov/pubmed/33876725
http://dx.doi.org/10.7554/eLife.68128

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