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The BHMT-betaine methylation pathway epigenetically modulates oligodendrocyte maturation

Research into the epigenome is of growing importance as a loss of epigenetic control has been implicated in the development of neurodegenerative diseases. Previous studies have implicated aberrant DNA and histone methylation in multiple sclerosis (MS) disease pathogenesis. We have previously reporte...

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Detalles Bibliográficos
Autores principales: Sternbach, Sarah, West, Nicole, Singhal, Naveen K., Clements, Robert, Basu, Soumitra, Tripathi, Ajai, Dutta, Ranjan, Freeman, Ernest J., McDonough, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112889/
https://www.ncbi.nlm.nih.gov/pubmed/33975330
http://dx.doi.org/10.1371/journal.pone.0250486