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Involvement of circRNAs in Proinflammatory Cytokines-Mediated β-Cell Dysfunction
AIM: During the initial stage of type 1 diabetes, prolonged exposure of pancreatic β-cell to proinflammatory cytokines such as IL-1β, TNF-α, and IFN-γ results in a decreased capacity to produce and release insulin, as well as cell loss by apoptosis. Circular RNAs (circRNAs) are a new class of endoge...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112919/ https://www.ncbi.nlm.nih.gov/pubmed/34054343 http://dx.doi.org/10.1155/2021/5566453 |