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Circadian time series proteomics reveals daily dynamics in cartilage physiology

OBJECTIVE: Cartilage in joints such as the hip and knee experiences repeated phases of heavy loading and low load recovery during the 24-h day/night cycle. Our previous work has shown 24 h rhythmic changes in gene expression at transcript level between night and day in wild type mouse cartilage whic...

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Detalles Bibliográficos
Autores principales: Dudek, M., Angelucci, C., Pathiranage, D., Wang, P., Mallikarjun, V., Lawless, C., Swift, J., Kadler, K.E., Boot-Handford, R.P., Hoyland, J.A., Lamande, S.R., Bateman, J.F., Meng, Q.-J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders For The Osteoarthritis Research Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113022/
https://www.ncbi.nlm.nih.gov/pubmed/33610821
http://dx.doi.org/10.1016/j.joca.2021.02.008