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Redox regulation of the insulin signalling pathway
The peptide hormone insulin is a key regulator of energy metabolism, proliferation and survival. Binding of insulin to its receptor activates the PI3K/AKT signalling pathway, which mediates fundamental cellular responses. Oxidants, in particular H(2)O(2), have been recognised as insulin-mimetics. Tr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113030/ https://www.ncbi.nlm.nih.gov/pubmed/33893069 http://dx.doi.org/10.1016/j.redox.2021.101964 |