Retinal oxidative stress activates the NRF2/ARE pathway: An early endogenous protective response to ocular hypertension

Oxidative stress contributes to degeneration of retinal ganglion cells and their axons in glaucoma, a leading cause of irreversible blindness worldwide, through sensitivity to intraocular pressure (IOP). Here, we investigated early elevations in reactive oxygen species (ROS) and a role for the NRF2-...

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Detalles Bibliográficos
Autores principales: Naguib, Sarah, Backstrom, Jon R., Gil, Melanie, Calkins, David J., Rex, Tonia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113046/
https://www.ncbi.nlm.nih.gov/pubmed/33579667
http://dx.doi.org/10.1016/j.redox.2021.101883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113046/
https://www.ncbi.nlm.nih.gov/pubmed/33579667
http://dx.doi.org/10.1016/j.redox.2021.101883

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