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TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma

Subependymomas are benign tumors characteristically encountered in the posterior fossa of adults that show distinct epigenetic profiles assigned to the molecular group “subependymoma, posterior fossa” (PFSE) of the recently established DNA methylation-based classification of central nervous system t...

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Detalles Bibliográficos
Autores principales: Thomas, Christian, Thierfelder, Felix, Träger, Malte, Soschinski, Patrick, Müther, Michael, Edelmann, Dominic, Förster, Alexandra, Geiler, Carola, Kim, Hee-yeong, Filipski, Katharina, Harter, Patrick N., Schittenhelm, Jens, Eckert, Franziska, Ntoulias, Georgios, May, Sven-Axel, Stummer, Walter, Onken, Julia, Vajkoczy, Peter, Schüller, Ulrich, Heppner, Frank L., Capper, David, Koch, Arend, Kaul, David, Paulus, Werner, Hasselblatt, Martin, Schweizer, Leonille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113189/
https://www.ncbi.nlm.nih.gov/pubmed/33755803
http://dx.doi.org/10.1007/s00401-021-02300-8