Creating a human-induced pluripotent stem cell-based NKX2.5 reporter gene assay for developmental toxicity testing

To test large numbers of chemicals for developmental toxicity, rapid in vitro tests with standardized readouts for automated data acquisition are needed. However, the most widely used assay, the embryonic stem cell test, relies on the counting of beating embryoid bodies by visual inspection, which i...

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Detalles Bibliográficos
Autores principales: Lauschke, Karin, Treschow, Andreas Frederik, Rasmussen, Mikkel Aabech, Davidsen, Nichlas, Holst, Bjørn, Emnéus, Jenny, Taxvig, Camilla, Vinggaard, Anne Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
In Vitro Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113199/
https://www.ncbi.nlm.nih.gov/pubmed/33660062
http://dx.doi.org/10.1007/s00204-021-03018-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113199/
https://www.ncbi.nlm.nih.gov/pubmed/33660062
http://dx.doi.org/10.1007/s00204-021-03018-y

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