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Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model

Exposure to cigarette smoke (CS) is a known risk factor in the pathogenesis of smoking-caused diseases, such as chronic obstructive pulmonary diseases (COPD) and lung cancer. To assess the effects of CS on the function and phenotype of airway epithelial cells, we developed a novel repeated treatment...

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Detalles Bibliográficos
Autores principales: Xiong, Rui, Wu, Yue, Wu, Qiangen, Muskhelishvili, Levan, Davis, Kelly, Tripathi, Priya, Chen, Ying, Chen, Tao, Bryant, Matthew, Rosenfeldt, Hans, Healy, Sheila M., Cao, Xuefei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113308/
https://www.ncbi.nlm.nih.gov/pubmed/33660061
http://dx.doi.org/10.1007/s00204-021-03008-0