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Molecular evolution and the decline of purifying selection with age

Life history theory predicts that the intensity of selection declines with age, and this trend should impact how genes expressed at different ages evolve. Here we find consistent relationships between a gene’s age of expression and patterns of molecular evolution in two mammals (the human Homo sapie...

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Detalles Bibliográficos
Autores principales: Cheng, Changde, Kirkpatrick, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113359/
https://www.ncbi.nlm.nih.gov/pubmed/33976227
http://dx.doi.org/10.1038/s41467-021-22981-9