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Optimization of Thymoquinone-Loaded Self-Nanoemulsion for Management of Indomethacin-Induced Ulcer

To improve the water solubility of thymoquinone (TQ), a major constituent of Nigella sativa seed oil, a TQ-loaded self-nanoemulsifying drug delivery system (SNEDDS) was prepared. The SNEDDS formulation was optimized using almond oil (AO) (Oil; X1), tween 80 (surfactant; X2) and polyethylene glycol 2...

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Detalles Bibliográficos
Autores principales: Radwan, Mohamed F., El-Moselhy, Mohamed A., Alarif, Walied M., Orif, Mohamed, Alruwaili, Nabil K., Alhakamy, Nabil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113367/
https://www.ncbi.nlm.nih.gov/pubmed/33994890
http://dx.doi.org/10.1177/15593258211013655