EGFR phosphorylates HDAC1 to regulate its expression and anti-apoptotic function

HDAC1 is the prototypical human histone deacetylase (HDAC) enzyme responsible for catalyzing the removal of acetyl group from lysine residues on many substrate proteins. By deacetylating histones and non-histone proteins, HDAC1 has a profound effect on the regulation of gene transcription and many p...

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Detalles Bibliográficos
Autores principales: Bahl, Sonali, Ling, Hongbo, Acharige, Nuwan P. N., Santos-Barriopedro, Irene, Pflum, Mary Kay H., Seto, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113371/
https://www.ncbi.nlm.nih.gov/pubmed/33976119
http://dx.doi.org/10.1038/s41419-021-03697-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113371/
https://www.ncbi.nlm.nih.gov/pubmed/33976119
http://dx.doi.org/10.1038/s41419-021-03697-6

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