Cell-Type Specific Changes in DNA Methylation of SNCA Intron 1 in Synucleinopathy Brains

Parkinson’s disease (PD) and dementia with Lewy body (DLB) are the most common synucleinopathies. SNCA gene is a major genetic risk factor for these diseases group, and dysregulation of its expression has been implicated in the genetic etiologies of several synucleinopathies. DNA methylation at CpG...

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Detalles Bibliográficos
Autores principales: Gu, Jeffrey, Barrera, Julio, Yun, Young, Murphy, Susan K., Beach, Thomas G., Woltjer, Randy L., Serrano, Geidy E., Kantor, Boris, Chiba-Falek, Ornit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113398/
https://www.ncbi.nlm.nih.gov/pubmed/33994928
http://dx.doi.org/10.3389/fnins.2021.652226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113398/
https://www.ncbi.nlm.nih.gov/pubmed/33994928
http://dx.doi.org/10.3389/fnins.2021.652226

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