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Structural visualization of transcription activated by a multidrug-sensing MerR family regulator

Bacterial RNA polymerase (RNAP) holoenzyme initiates transcription by recognizing the conserved –35 and –10 promoter elements that are optimally separated by a 17-bp spacer. The MerR family of transcriptional regulators activate suboptimal 19–20 bp spacer promoters in response to myriad cellular sig...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Liu, Chang, Zhou, Wei, Shi, Wei, Chen, Ming, Zhang, Baoyue, Schatz, David G., Hu, Yangbo, Liu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113463/
https://www.ncbi.nlm.nih.gov/pubmed/33976201
http://dx.doi.org/10.1038/s41467-021-22990-8