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Depletion of kinesin motor KIF20A to target cell fate control suppresses medulloblastoma tumour growth

During mammalian brain development, neural progenitor cells proliferate extensively but can ensure the production of correct numbers of various types of mature cells by balancing symmetric proliferative versus asymmetric differentiative cell divisions. This process of cell fate determination may be...

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Detalles Bibliográficos
Autores principales: Qiu, Runxiang, Wu, Jun, Gudenas, Brian, Northcott, Paul A., Wechsler-Reya, Robert J., Lu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113472/
https://www.ncbi.nlm.nih.gov/pubmed/33976373
http://dx.doi.org/10.1038/s42003-021-02075-4